BIOCH 606 Physiological Chemistry 3(3,0) Chemical basis of the mammalian physiological processes of muscle contraction, nerve function, respiration, kidney function, and blood homeostasis is studied. Composition of specialized tissue such as muscle, nerve, blood, and bone; regulation of water, electrolytes, and acid-base balance are discussed. Preq: BIOCH 305 or Organic Chemistry.
BIOCH 623 Principles of Biochemistry 3(3,0) Study of the chemistry of amino acids, monosaccharides, fatty acids, purines, pyrimidines, and associated compounds leads to an understanding of their properties and the relationship between structure and function that makes them important in biological processes. The use of modern techniques is stressed. Preq: CH 224 or equivalent.
BIOCH 631 Physical Approach to Biochemistry 3(3,0) Study of chemical and physical properties of amino acids, lipids, nucleic acids, sugars, and their biopolymers. Physical and mathematical analyses are correlated with biological structure and function. Preq: BIOCH 301 with a C or better or consent of instructor. Coreq: Physical Chemistry.
BIOCH 632 Biochemistry of Metabolism 3(3,0) Study of central pathways of carbohydrate, lipid, and nucleotide metabolism. Bioenergetics, limiting reactions, and the regulation and integration of the metabolic pathways are emphasized. Preq: BIOCH 423 or 431 or consent of instructor.
BIOCH 633 General Biochemistry Laboratory I 2(0,4) Experiments selected to illustrate current methods used in biochemical research. Coreq: BIOCH 423 or 431.
BIOCH 634 General Biochemistry Laboratory II 2(0,4) Continuation of BIOCH 433. Preq: Concurrent enrollment in BIOCH 432.
BIOCH 636 Nucleic Acid and Protein Biosynthesis 3(3,0) Examines how nucleic acids and proteins are synthesized in prokaryotic and eukaryotic cells. Designed for students interested in biochemistry, cell biology, molecular biology, and cell physiology. Preq: BIOCH 423, 431 or 432 or consent of instructor.
BIOCH 643 Biochemical Basis of Disease 3(3,0) Topics in heritable human metabolic disorders including clinical features and newborn screening, genetic testing, the biochemical basis, and treatment. Preq: BIOCH 301, GEN 302, or consent of instructor.
BIOCH (GEN) 805 Issues in Research 2(2,0) Scientific writing, oral presentations, and critical evaluation of them; legal and ethical issues associated with modern biochemical research. Science job hunting, time management, and creativity for professional scientists are treated. Preq: Graduate enrollment in Biochemistry and Molecular Biology or consent of instructor.
BIOCH (GEN) 810 Methods in Molecular Biology 5(3,6) Study of prokaryotic and eukaryotic gene structure, regulation of transcription initiation, regulation of protein synthesis, and analysis of protein function. Laboratory provides intensive hands-on experience using techniques that allow dissection of these processes. Preq: Enrollment in Genetics or in Biochemistry and Molecular Biology or consent of instructor.
BIOCH 814 Advanced Biochemistry 3(3,0) Contemporary topics of functional and cellular aspects in biochemistry with particular focus on new observations, emerging ideas, and important techniques. Preq: Two-semester sequence in biochemistry or consent of instructor.
BIOCH 815 Lipids and Biomembranes 3(3,0) Isolation, chemical and physical properties, and metabolism of lipids; purification, structure, function, and biosynthesis of biomembranes. Preq: BIOCH 632 or consent of instructor.
BIOCH 816 Signal Transduction 3(3,0) Characteristics and components of signal transduction processes in model species of plants, animals, and microbes. Preq: BIOCH (GEN) 810 and GEN (BIOCH) 820, or consent of instructor.
BIOCH 818 Cellular Metabolism 3(3,0) Evolution, regulation, characterization, and manipulation of metabolic pathways. Preq: BIOCH 814 and GEN (BIOCH) 820, or consent of instructor.
BIOCH (GEN) 820 Genomics and Proteomics 5(5,0) See GEN 820.
BIOCH 821 Proteins 3(3,0) Isolation, composition, structure, and properties of proteins; methods of isolation, analysis, and characterization; properties of "unusual" protein systems. Preq: BIOCH 623 or 631 or consent of instructor.
BIOCH 822 Enzymes 3(3,0) Kinetics, mechanisms of action, inhibitions, and general properties of enzymes. Preq: BIOCH 623 or 631.
BIOCH (GEN) 825 Seminar I 1(1,0) See GEN 825.
BIOCH 828 Supramolecular Structure 3(3,0) Cellular structures like viruses, ribosomes, and various membrane systems, including rafts and some organelles, are described using modern methods of structural characterization. The methods and the theory of the methods are discussed along with the structures and their functions. Preq: BIOCH 814 or consent of the instructor.
BIOCH 831 Physical Biochemistry 3(3,0) Description and theory of physical methods and instrumentation used in analysis of biological macromolecules. Preq: BIOCH 623 or 631, one semester of physical chemistry, or consent of instructor.
BIOCH 832 Structure and Function of Nucleic Acids 3(3,0) Physical, chemical, and biochemical properties of nucleotides, oligonucleotides, RNA, and DNA; antisense oligonucleotides and aptmers; unusual structures of RNA and DNA; nucleic acids-protein interactions; nucleic acids-metal interactions; small RNAs and RNA interference; catalytic nucleic acids; nucleic acids repair. Preq: BIOCH 814 or GEN 814 or consent of instructor.
BIOCH 841 Biochemical Genetics 3(3,0) Regulation of replication and transcription. Students present papers from recent literature and write a research proposal. Preq: One year of biochemistry or consent of instructor.
BIOCH (GEN) 851 Seminar II 1(1,0) Current topics in biochemistry.
BIOCH 890 Special Topics in Biochemistry 1-6(1-6,0) Group discussions of recent developments in biochemical research. May be repeated for a maximum of six credits, but only if different topics are covered. Preq: BIOCH 814 or consent of instructor.
BIOCH 891 Master's Thesis Research 1-12
BIOCH 991 Doctoral Dissertation Research 1-12