BIO E (C M E) 680 Research Principles and Concepts 1(1,0) Introduces seniors and graduate students to principles and practices of scientific research. Topics include developing scientific concepts, developing projects, pursuing research, collaborating in multidisciplinary teams, patenting and publishing technical and scientific information, and reviewing professional and ethical standards of performance. To be taken Pass/Fail only.
BIO E 800 Seminar in Bioengineering Research 1(2,0) Original research in bioengineering; weekly one-hour seminar associated with weekly recitation covering seminar preparation, presentation, professional writing, bioengineering ethics, and related topics. To be taken Pass/Fail only.
BIO E 801 Biomaterials 3(3,0) Structure and properties of the main classes of materials used in artificial organs and surgical implants; metals, ceramics, polymers, composites, and materials of biological origin; mechanical properties, corrosion, and design. Preq: Consent of instructor.
BIO E 802 Compatibility of Biomaterials 3(1,6) Determining compatibility of biomaterials with the physiological environment; optical microscopy, microradiography, and ultraviolet fluorescence; normal histology of tissues, basic pathological reactions, and tissue reactions to materials.
BIO E 803 Polymeric Biomaterials 3(3,0) Interplay of physicochemical properties of polymeric materials and the design of biomedical devices and their in vitro and in vivo performance; critical manufacturing aspects of selected augmentation and prosthetic devices for soft and hard tissues; analysis of case studies and reports on recent research findings. Preq: Consent of instructor.
BIO E 804 Metallic and Ceramic Implant Materials 3(3,0) Interaction between implant material and host tissue, selection of materials for different applications, influences of material and host tissue performance on implant design and on in vitro testing of implant materials and devices. Preq: BIO E 801 and consent of instructor.
BIO E 807 Nanotechnology and Biomaterials 3(3,0) Emerging field of nanotechnology and its relation to solving bioengineering and health-related problems is treated. The promise of nano-technology in the creation and utilization of materials and devices at the level of atoms and molecules. New scientific approaches, research tools, clinical tools, and devices are presented.
BIO E 812 Orthopedic Engineering and Pathology 3(3,0) Interdisciplinary study of orthopedic cases (bone growth, bone remodeling, osteoarthritis, implant fixation, and joint replacements); biomechanical, biomaterials, and clinical diagnosis of failed implants (total joints, fracture fixation, and spinal instrumentation); basic concepts of orthopedic pathology for engineers. Preq: BIO E 801, 802, 820, and 882, or consent of instructor.
BIO E 820 Structural Biomechanics 3(3,0) Mechanical functions of the human body treated as an engineering structure and the devices used to assist and supplement these functions; movement of the musculoskeletal system; locomotion; gait; prehension; lifting; function of artificial limbs; orthopedic prostheses and braces; effect of vibration and impact on the body; mathematical and other models of the body. Preq: Consent of instructor.
BIO E 823 Vascular Engineering and Pathology 2(2,0) Medical and bioengineering aspects of artificial vascular and cardiovascular devices; physiology and pathological aspects of patients with need for such devices; diagnostic techniques and surgical management of diseases and pathology; design aspects of current devices and selection; state-of-the-art in experiments and human clinical trials. Preq: BIO E 801, 802, and 846, or consent of instructor.
BIO E 846 Biomedical Basis for Engineered Replacement 3(3,0) Form and function of human organs, major systems, and examples of engineering repair and replacement methods are presented in light of pathological or traumatic organ malfunction. Core course for all Bioengineering graduate students, taken preferably during their first fall semester.
BIO E 847 Transport Processes in Bioengineering 4(4,0) Cardiovascular systems and regulation; physiology of blood, heart, and organ blood flow; properties of blood as a fluid; fluid flow equations; turbulence; pulse propagation; respiration and control of breathing; gas exchange; heart-lung bypass devices; renal function and control; artificial kidney devices; heat flow and temperature regulation. Preq: BIOSC 459.
BIO E 848 Cellular Interactions with Biomate-rials 4(2,2) Cell biological concepts and issues relevant to cell-biomaterial interactions; methods for studying cell structure and function including basic cell culture techniques and in vitro biocompatibility analyses; biomaterial physio-chemical properties which influence cellular interactions; interactions between implant materials and host tissues at the cellular and molecular level; overview of tissue engineering.
BIO E 849 Tissue Engineering 3(3,0) Principles and practices of bioartificial organ and tissue development; cellular/material interaction and translation of information from two-dimensional surfaces to three-dimensional scaffolds; selection and processing of biomaterials to form tissue scaffolds; analysis of tissue engineered devices, standards, and regulation. Preq: BIO E 801, 846.
BIO E 850 Selected Topics in Biomedical Engineering 1-4(0-4,12-0) Advanced topics in bioengineering intended to develop in-depth areas of particular student interest. Credit may be earned for more than one semester. Preq: Consent of instructor.
BIO E 870 Bioinstrumentation 3(2,2) Concepts and techniques of instrumentation in bioengineering emphasizing effects of instrumentation on the biological system under investigation; transducers and couplers; data conversion; conditioning and transmission; experimental problems in acute and chronic procedures with static and dynamic subjects.
BIO E 882 Biomaterials Implantology 4(2,6) All phases of experimental surgery including selection of animal models, preparation of animals for surgery, general and special surgical techniques, and basic and applied instrumentation. Preq: BIOSC 459 or equivalent.
BIO E 890 Internship 1-5 Observation and assignment in a medical college, dental college, hospital, veterinary clinic, dental clinic, health service, or industrial department. Preq: Consent of department chair.
BIO E 891 Master's Thesis Research 1-12
BIO E 892 Nonthesis Independent Study in Bio-engineering 1-6 Independent study in bioengineering for work necessary to complete requirements for the Master of Science degree in Bioengineering, nonthesis option. May be repeated for additional credit. To be taken Pass/Fail only.
BIO E 991 Doctoral Dissertation Research 1-12